We are in constant pursuit of breakthroughs that change patients' lives. We innovate every day to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies deliver better results, are more inventive, draw and keep the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—drives everything we do and shows our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and represents the value we aim to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We fulfill our purpose by seeking the best science in the world, collaborating with others in the healthcare system to increase access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.